Formulation and Evaluation of Stable Solid Dispersion of Anti-Protozoal Drug

摘要

ABSTRACT The solubility behaviour of drug is one of most challenging aspect in formulation development. Thus a greater understanding of dissolution & absorption behaviour of drug with low aqueous solubility is required to successfully formulate them into more soluble and hence bioavailable drug product. The current investigation includes formulating solid dispersions of Tinidazole, an antiprotozoal and antiamoebic drug which is characterized by poor solubility and rapid absorption (BCS-2). Thus.