Acetylation and methylation patterns of core histones are modified after heat or arsenite treatment of Drosophila tissue culture cells

摘要

Exposure of Drosophila melanogaster tissue culture cells to 37°C (heat shock) or to arsenite induces a severe deacetyl-ation of core histones and blocks the methylation of histone H₃ and H₄. Heat shock induces the methylation of histone H_2b. These results are discussed in view of chromatin structure and function.