Lecithinized superoxide dismutase reduces cold ischemia-induced chronic allograft dysfunction

摘要

Lecithinized superoxide dismutase reduces cold ischemia-induced chronic allograft dysfunction.BackgroundChronic renal allograft failure (CAF) is influenced by both allo-dependent and independent factors and is a major cause of graft loss in clinical renal transplantation. We evaluated a novel membrane-bound free radical scavenger, lecithinized superoxide dismutase (lec-SOD), to determine its potential in limiting the harmful effects of ischemia/reperfusion injury on CAF.