Generic synthesis of small-sized hollow mesoporous organosilica nanoparticles for oxygen-independent X-ray-activated synergistic therapy

Wenpei Fan; Nan Lu; Zheyu Shen; Wei Tang; Bo Shen; Zhaowen Cui; Lingling Shan; Zhen Yang; Zhantong Wang; Orit Jacobson; Zijian Zhou; Yijing Liu; Ping Hu; Weijing Yang; Jibin Song; Yang Zhang; Liwen Zhang; Niveen M. Khashab; Maria A. Aronova; Guangming Lu; Xiaoyuan Chen

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Generic synthesis of small-sized hollow mesoporous organosilica nanoparticles for oxygen-independent X-ray-activated synergistic therapy

机译：小型中空介孔有机二氧化硅纳米粒子的通用合成，用于不依赖氧的X射线活化协同治疗

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co-loaded PEGylated HMONs without reliance on oxygen, which brings about remarkable destructive effects against both normoxic and hypoxic cancers.

机译：在不依赖氧气的情况下共装载了聚乙二醇化的HMON，这对常氧和低氧癌症均具有显着的破坏作用。

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《Nature Communications》 |2019年第1期|共14页
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Wenpei Fan; Nan Lu; Zheyu Shen; Wei Tang; Bo Shen; Zhaowen Cui; Lingling Shan; Zhen Yang; Zhantong Wang; Orit Jacobson; Zijian Zhou; Yijing Liu; Ping Hu; Weijing Yang; Jibin Song; Yang Zhang; Liwen Zhang; Niveen M. Khashab; Maria A. Aronova; Guangming Lu; Xiaoyuan Chen;
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1. Hollow Mesoporous Organosilica Nanoparticles: A Generic Intelligent Framework-Hybridization Approach for Biomedicine [J] . Yu Chen, Qingshuo Meng, Meiying Wu, Journal of the American Chemical Society . 2014,第46期

机译：空心介孔有机硅纳米粒子：生物医学的通用智能框架-杂交方法。
2. Acidity/Reducibility Dual-Responsive Hollow Mesoporous Organosilica Nanoplatforms for Tumor-Specific Self-Assembly and Synergistic Therapy (vol 12, pg 12269, 2018) [J] . Tang Wei, Fan Wenpei, Wang Zhantong, ACS nano . 2019,第5期

机译：酸度/再减产性双响应中空介孔有机纳米纳米纳薄纳米纳薄机构用于肿瘤特异性自组装和协同疗法（Vol 12，PG 12269,2018）
3. Acidity/Reducibility Dual-Responsive Hollow Mesoporous Organosilica Nanoplatforms for Tumor-Specific Self-Assembly and Synergistic Therapy [J] . Tang Wei, Fan Wenpei, Wang Zhantong, ACS nano . 2018,第12期

机译：酸度/再减产性双响应中空介孔有机吲哚美纳纳薄瘤，用于肿瘤特异性自组装和协同疗法
4. Synergistic combination cancer therapy based in lectin-targeted pH-responsive mesoporous silica nanoparticles [C] . Marina Martinez-Carmona, Montserrat Colilla, Daniel Lozano, World biomaterials congress . 2016

机译：基于凝集素靶向的pH响应介孔二氧化硅纳米粒子的协同联合癌症治疗
5. Synthesis, Characterization and Catalytic Studies of N-Doped Ordered Mesoporous Carbons and Functionalized Periodic Mesoporous Organosilicas [D] . Parikh, Bosky. 2017

机译：N掺杂有序介孔碳和功能化周期性介孔有机硅的合成，表征和催化研究
6. Generic synthesis of small-sized hollow mesoporous organosilica nanoparticles for oxygen-independent X-ray-activated synergistic therapy [O] . Wenpei Fan, Nan Lu, Zheyu Shen, -1

机译：小型中空介孔有机二氧化硅纳米粒子的通用合成用于不依赖氧的X射线活化协同治疗
7. Nanoparticles: Large Pore-Sized Hollow Mesoporous Organosilica for Redox-Responsive Gene Delivery and Synergistic Cancer Chemotherapy (Adv. Mater. 10/2016) [O] . Meiying Wu, Qingshuo Meng, Yu Chen, 2016

机译：纳米粒子：大孔径中空介孔有机剂用于氧化还原响应基因递送和协同癌症化疗（ADV。Mater。10/2016）

Generic synthesis of small-sized hollow mesoporous organosilica nanoparticles for oxygen-independent X-ray-activated synergistic therapy

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