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首页> 外文期刊>Molecules >New Alcamide and Anti-oxidant Activity of Pilosocereus gounellei A. Weber ex K. Schum. Bly. ex Rowl. (Cactaceae)
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New Alcamide and Anti-oxidant Activity of Pilosocereus gounellei A. Weber ex K. Schum. Bly. ex Rowl. (Cactaceae)

机译:Pilosocereus gounellei A. Weber出自K. Schum的新的Alcamide和抗氧化活性。拜利前罗尔。 (仙人掌科)

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摘要

The Cactaceae family is composed by 124 genera and about 1438 species. Pilosocereus gounellei , popularly known in Brazil as xique-xique, is used in folk medicine to treat prostate inflammation, gastrointestinal and urinary diseases. The pioneering phytochemical study of P. gounellei was performed using column chromatography and HPLC, resulting in the isolation of 10 substances: pinostrobin ( 1 ), β-sitosterol ( 2 ), a mixture of sitosterol 3- O -β- d -glucopyranoside/stigmasterol 3- O -β- d -glucopyranoside ( 3a / 3b ), 13 2 -hydroxyphaeophytin a ( 4 ), phaeophytin a ( 5 ), a mixture of β-sitosterol and stigmasterol ( 6a / 6b ), kaempferol ( 7 ), quercetin ( 8 ), 7′-ethoxy- trans -feruloyltyramine (mariannein, 9 ) and trans -feruloyl tyramine ( 10 ). Compound 9 is reported for the first time in the literature. The structural characterization of the compounds was performed by analyses of 1-D and 2-D NMR data. In addition, a phenolic and flavonol total content assay was carried out, and the anti-oxidant potential of P. gounellei was demonstrated.
机译:仙人掌科由124属和大约1438种组成。 Pilosocereus gounellei,在巴西俗称xique-xique,在民间医学中用于治疗前列腺炎,胃肠道和泌尿系统疾病。使用柱色谱和HPLC进行了古氏疟原虫的开创性植物化学研究,分离出10种物质:松油菌素(1),β-谷甾醇(2),谷甾醇3-O-β-d-吡喃葡萄糖苷/豆甾醇3-O-β-d-吡喃葡萄糖苷(3a / 3b),13 2-羟基邻苯二酚a(4),邻苯二酚a(5),β-谷固醇和豆甾醇(6a / 6b)的混合物,山fer酚(7),槲皮素(8),7'-乙氧基-反式-feruloyltyramine(mariannein,9)和反式-阿魏酰酪胺(10)。化合物9在文献中首次报道。通过分析1-D和2-D NMR数据进行化合物的结构表征。另外,进行了酚类和黄酮醇的总含量测定,并证明了冈氏疟原虫的抗氧化潜力。

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