QUAL2K model is used to simulate the water quality of Wei River and the verification results are analyzed in this paper. For the actual situation of pollution in Wei River Basin, COD, ammonia nitrogen and total phosphorus are chosen as indexes of water quality prediction. The degradation coefficient of them, being one important water quality parameter, is calculated as 0.2428, 0.1019 and 0.2554, respectively. Conduct parameter setting and compared with the measured values combining comprehensive one-dimensional water quality model formula, with the measured data, then make adjustments to get new degradation coefficient with the values are 0.3631, 0.2046 and 0.2545, respectively. The simulation results are verified and showed that the predicted values fit with the measured ones well, the relative errors of COD, ammonia nitrogen and total phosphorus concentration are within 10%, and the simulation effect is good.
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