首页> 外文期刊>Genetics: A Periodical Record of Investigations Bearing on Heredity and Variation >Ninety-Six Haploid Yeast Strains With Individual Disruptions of Open Reading Frames Between YOR097C and YOR192C, Constructed for the Saccharomyces Genome Deletion Project, Have an Additional Mutation in the Mismatch Repair Gene MSH3
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Ninety-Six Haploid Yeast Strains With Individual Disruptions of Open Reading Frames Between YOR097C and YOR192C, Constructed for the Saccharomyces Genome Deletion Project, Have an Additional Mutation in the Mismatch Repair Gene MSH3

机译:为酵母基因组缺失项目构建的九十六个单倍体酵母菌株,其在YOR097C和YOR192C之间的开放阅读框被单独破坏,在错配修复基因MSH3中有一个额外的突变

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摘要

As part of the Saccharomyces Genome Deletion Project, sets of presumably isogenic haploid and diploid strains that differed only by single gene deletions were constructed. We found that one set of 96 strains (containing deletions of ORFs located between YOR097C and YOR192C ) in the collection, which was derived from the haploid BY4741, has an additional mutation in the MSH3 mismatch repair gene.
机译:作为酵母基因组缺失项目的一部分,构建了仅由单个基因缺失而不同的大概同基因的单倍体和二倍体菌株。我们发现集合中的一组96株(包含位于YOR097C和YOR192C之间的ORF的缺失)来源于单倍体BY4741,在MSH3错配修复基因中有一个额外的突变。

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