Targeting CD4+ CD25+ FOXP3+ Treg cells abrogates established mechanisms of immune tolerance, reshuffles the T cell repertoire and results in effective anti-tumor immunity

S.Rolla; S.Occhipinti; R.Cojoca; M.Spadaro; R.Penitente; F.Ria; F.Cavallo

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Targeting CD4+ CD25+ FOXP3+ Treg cells abrogates established mechanisms of immune tolerance, reshuffles the T cell repertoire and results in effective anti-tumor immunity

机译：靶向CD4 + CD25 + FOXP3 + Treg细胞可废除已建立的免疫耐受机制，改组T细胞库并产生有效的抗肿瘤免疫力

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《European Journal of Cancer Supplements》 |2008年第9期|共2页
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S.Rolla; S.Occhipinti; R.Cojoca; M.Spadaro; R.Penitente; F.Ria; F.Cavallo;
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中图分类肿瘤学;
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1. Targeting CD4+ CD25+ FOXP3+ Treg cells abrogates established mechanisms of immune tolerance, reshuffles the T cell repertoire and results in effective anti-tumor immunity [J] . S.Rolla, S.Occhipinti, R.Cojoca, European Journal of Cancer Supplements . 2008,第9期

机译：靶向CD4 + CD25 + FOXP3 + Treg细胞可废除已建立的免疫耐受机制，改组T细胞库并产生有效的抗肿瘤免疫力
2. Gold nanorods enhance different immune cells and allow for efficient targeting of CD4+ Foxp3+ Tregulatory cells [J] . Ingrid Safina, Zeid A. Nima Al Sudani, Ahmed Hashoosh, PLoS One . 2021,第8期

机译：金纳米棒增强不同的免疫细胞，允许有效靶向CD4 + Foxp3 +特定细胞
3. Breaking immune tolerance by targeting CD25+ regulatory T cells is essential for the anti-tumor effect of the CTLA-4 blockade in an HLA-DR transgenic mouse model of prostate cancer [J] . KlyushnenkovaE.N., RiabovV.B., KouiavskaiaD.V., The Prostate . 2014,第14期

机译：通过靶向CD25 +调节性T细胞来打破免疫耐受性对于前列腺癌HLA-DR转基因小鼠模型中CTLA-4阻断的抗肿瘤作用至关重要
4. Photodynamic therapy stimulates anti-tumor immune response in mouse models: the role of regulatory T-cells, anti-tumor antibodies, and immune attack on brain metastases [C] . Fatma Vatansever, Masayoshi Kawakubo, Hoon Chung, Biophotonics and immune responses VIII . 2013

机译：光动力疗法在小鼠模型中刺激抗肿瘤免疫反应：调节性T细胞，抗肿瘤抗体的作用以及对脑转移瘤的免疫攻击
5. Interactions between antigen presenting cells and CD4+ T cells in the generation of anti-tumor immunity. [D] . Brown, Deborah Martha. 2002

机译：抗原呈递细胞与CD4 + T细胞之间的相互作用产生了抗肿瘤免疫力。
6. Hepatocellular carcinoma in viral and autoimmune liver diseases: Role of CD4+ CD25+ Foxp3+ regulatory T cells in the immune microenvironment [O] . Alessandro Granito, Luigi Muratori, Claudine Lalanne, 2021

机译：病毒和自身免疫性肝脏疾病的肝细胞癌：CD4 + CD25 + Foxp3 +调节T细胞在免疫微环境中的作用
7. TLR2-dependent induction of IL-10 and Foxp3+ CD25+ CD4+ regulatory T cells prevents effective anti-tumor immunity induced by Pam2 lipopeptides in vivo. [O] . Sayuri Yamazaki, Kohei Okada, Akira Maruyama, 2011

机译：IL-10和Foxp3 + CD25 + CD4 +调节性T细胞的TLR2依赖性诱导阻止pam2脂肽在体内诱导的有效抗肿瘤免疫。

Targeting CD4+ CD25+ FOXP3+ Treg cells abrogates established mechanisms of immune tolerance, reshuffles the T cell repertoire and results in effective anti-tumor immunity

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