29 A phase I pharmacokinetic (PK) and pharmacodynamic (PD) study of OGX-011, a 2′-methoxyethyl phosphorothioate antisense to clusterin, in patients with prostate cancer prior to radical prostatectomy

K.N.Chi; E.Eisenhauer; L.Fazli; E.C.Jones; J.Powers; A.Hurtado-Coll; S.L.Goldenberg; M.E.Gleave

首页> 外文期刊>European Journal of Cancer Supplements >29 A phase I pharmacokinetic (PK) and pharmacodynamic (PD) study of OGX-011, a 2′-methoxyethyl phosphorothioate antisense to clusterin, in patients with prostate cancer prior to radical prostatectomy

【24h】

29 A phase I pharmacokinetic (PK) and pharmacodynamic (PD) study of OGX-011, a 2′-methoxyethyl phosphorothioate antisense to clusterin, in patients with prostate cancer prior to radical prostatectomy

机译：29 OGX-011的I期药代动力学（PK）和药效学（PD）研究，OGX-011是一种2'-甲氧基乙基硫代磷酸酯反聚簇蛋白，用于前列腺癌根治性前列腺切除术前的患者

获取原文

获取外文期刊封面封底 >>

开具论文收录证明 >>

文献代查 >>

团队文献服务 >>

页面导航

著录项
相似文献
相关主题

著录项

来源
《European Journal of Cancer Supplements 》 |2004年第8期| 共1页
作者
K.N.Chi; E.Eisenhauer; L.Fazli; E.C.Jones; J.Powers; A.Hurtado-Coll; S.L.Goldenberg; M.E.Gleave;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种
中图分类肿瘤学 ;
关键词

相似文献

外文文献
中文文献
专利

1. A phase I pharmacokinetic and pharmacodynamic study of OGX-011, a 2'-methoxyethyl antisense oligonucleotide to clusterin, in patients with localized prostate cancer. [J] . Chi KN, Eisenhauer E, Fazli L, Journal of the National Cancer Institute . 2005 ,第17期

机译：OGX-011（一种针对簇蛋白的2'-甲氧基乙基反义寡核苷酸）在局部前列腺癌患者中的I期药代动力学和药效学研究。
2. AZD8186 study 1: Phase I study to assess the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) and preliminary anti-tumour activity of AZD8186 in patients with advanced castration resistant prostate cancer (CRPC), squamous non-small cell lung cancer, triple negative breast cancer and with PTEN-deficient/mutated or PIK3CB mutated/amplified malignancies, as monotherapy and in combination with vistusertib (AZD2014) or abiraterone acetate [J] . Lillian S., De Bono J., Higano C., European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) . 2016 ,第Null期

机译：AZD8186研究1：I期研究评估AZD8186在晚期去势抵抗性前列腺癌（CRPC），鳞状非小细胞肺癌患者中的安全性，耐受性，药代动力学（PK），药效学（PD）和初步抗肿瘤活性，三联阴性乳腺癌以及PTEN缺陷/突变或PIK3CB突变/扩增的恶性肿瘤，单药治疗并与vistusertib（AZD2014）或醋酸阿比特龙合用
3. AZD8186 study 1: Phase I study to assess the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) and preliminary anti-tumour activity of AZD8186 in patients with advanced castration resistant prostate cancer (CRPC), squamous non-small cell lung cancer, triple negative breast cancer and with PTEN-deficient/mutated or PIK3CB mutated/amplified malignancies, as monotherapy and in combination with vistusertib (AZD2014) or abiraterone acetate [J] . Lillian S., De Bono J., Higano C., European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) . 2016 ,第Null期

机译：AZD8186研究1：I期研究，评估AZD8186在先进的阉割前列腺癌（CRPC），鳞状非小细胞肺癌患者中AZD8186的安全性，耐受性，药代动力学（PK），药效学（PD）和初步抗肿瘤活性，三重阴性乳腺癌和PTEN缺乏/突变或PIK3CB突变/扩增的恶性肿瘤，作为单药治疗，与Vistusertib（AZD2014）或乙酸酯组合
4. Framework for the co-registration of MRI and Histology Images in Prostate Cancer Patients with Radical Prostatectomy [C] . Mirabela Rusu, Christian Kunder, Richard Fan, Society of Photo-Optical Instrumentation Engineers;SPIE Medical Imaging Conference . 2019

机译：前列腺癌根治性前列腺切除术患者的MRI和组织学图像共同配准的框架
5. Evaluation of quality of life for prostate cancer patients who have undergone radical prostatectomy surgery. [D] . Tomicich, Stephen F. 2006

机译：接受前列腺癌根治术的前列腺癌患者的生活质量评估。
6. TEN-YEAR FOLLOW-UP OF NEOADJUVANT THERAPY WITH GOSERELIN ACETATE AND FLUTAMIDE PRIOR TO RADICAL PROSTATECTOMY FOR CLINICAL T3 AND T4 PROSTATE CANCER: UPDATE ON SOUTHWEST ONCOLOGY GROUP STUDY 9109 [O] . Ryan K. Berglund, Catherine M. Tangen, Isaac J. Powell, -1

机译：在临床T3和T4前列腺癌的自由基前列腺切除术前醋酸甘油苷和氟胺的十年随访氟氨酸癌：西南肿瘤学群体的更新9109
7. A Phase II, Randomized, Open-Label Study of Neoadjuvant Degarelix versus LHRH Agonist in Prostate Cancer Patients Prior to Radical Prostatectomy [O] . Rashid K. Sayyid, Andrew Evans, Karen Hersey, 2016

机译：在自由基前列腺切除术前前列腺癌患者的Neoadjuvant Degarix的II期，随机开放标签研究与前列腺癌患者的LHRH激动剂
8. Phase I/II Study of Combination Neoadjuvant Hormone Therapy and Weekly OGX-011 (Clusterin Antisense Oligonulceotide) Prior to Radical Prostatectomy in Patients with Localized Prostate Cancer [R] . Chi, K. N. 2008

机译：I / II期研究联合新辅助激素治疗和每周OGX-011（Clusterin反义寡核苷酸）前局部前列腺癌根治性前列腺切除术

29 A phase I pharmacokinetic (PK) and pharmacodynamic (PD) study of OGX-011, a 2′-methoxyethyl phosphorothioate antisense to clusterin, in patients with prostate cancer prior to radical prostatectomy

著录项

相似文献

相关主题

期刊订阅