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首页> 外文期刊>Emerging Infectious Diseases >Etymologia: Bonferroni Correction (http://wwwnc.cdc.gov/eid/article/21/2/et-2102)
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Etymologia: Bonferroni Correction (http://wwwnc.cdc.gov/eid/article/21/2/et-2102)

机译:病情:Bonferroni矫正(http://wwwnc.cdc.gov/eid/article/21/2/et-2102)

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Named after Italian mathematician Carlo Emilio Bonferroni (1892–1960) but first attributed to Olive Jean Dunn, the Bonferroni correction compensates for multiple comparisons by dividing the significance level by the number of comparisons. The significance level is the probability that a given test will incorrectly find a difference in the sample that is not present in the population (false positive). A significance level of 0.05 is a commonly accepted significance level. If a study tested 5 comparisons, there would be up to a 25% likelihood (0.05 + 0.05 + 0.05 + 0.05 + 0.05) that any one of them would show a significant difference by chance. The Bonferroni correction adjusts for this by dividing the significance level by the number of tests. In this case, the significance level for a given comparison would be 0.01, for an overall risk no larger than 0.05 of falsely detecting a difference.
机译:以意大利数学家卡洛·埃米利奥·邦费罗尼(Carlo Emilio Bonferroni,1892-1960年)命名,但最早归因于奥利夫·让·邓恩(Olive Jean Dunn),邦费罗尼校正通过将显着性水平除以比较次数来补偿多重比较。显着性水平是给定测试将错误地发现总体中不存在的样本差异的概率(假阳性)。 0.05的显着性水平是公认的显着性水平。如果一项研究测试了5个比较,那么任何一个偶然出现显着差异的可能性均高达25%(0.05 + 0.05 + 0.05 + 0.05 + 0.05)。 Bonferroni校正通过将显着性水平除以测试次数来对此进行调整。在这种情况下,对于给定比较的显着性水平为0.01,因为错误检测差异的总风险不大于0.05。

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