No Resistance Plasmid in Yersinia pestis, North America

摘要

To the Editor: Plague, caused by Yersinia pestis, is now largely con-trolled by improved sanitation and the use of antimicrobial drugs. However, before the widespread availability of antimicrobial drugs, an estimated >200 million persons died during pan-demics (1). Today, if Y. pestis were to acquire antimicrobial drug resistance determinants, plague could again be a deadly disease