Sporadic Oropouche Infection, Acre, Brazil

摘要

To the Editor: Oropouche virus (OROV), a member of the Bunya-viridae family, Orthobunyavirus ge-nus, Simbu serogroup, is transmitted to humans in urban areas by the bit-ing midge Culicoides paraensis and causes epidemic acute febrile disease (1). Since its fi rst isolation in Trinidad in 1955 (2), OROV has been associ-ated with large outbreaks in South and Central America; half a million cases have been described during the past 45 years (1). The tripartite genome of OROV comprises single-strand, neg-ative-sense large (L), medium (M), and small (S) RNAs that encode RNA polymerase, glycoproteins, and nu-cleocapsid, respectively. Studies have indicated the existence of 3 genotypes of OROV circulating in Brazil: geno-types I and II in the Amazon Basin and genotype III in the Southeast Region (3–5).