Fluoroquinolone Resistance and Clostridium difficile, Germany

摘要

We characterized 670 Clostridium diffi cile isolates col-lected from patients in 84 hospitals in Germany in 2008. PCR ribotyping showed high prevalence of ribotype 001 and restricted dissemination of ribotype 027 strains. Fluo-roquinolone resistance and associated gyrase mutations were frequent in various ribotypes, but no resistance to met-ronidazole or vancomycin was noted