To the Editor: Corynebacterium diphtheriae is the agent of pharyngeal and cutaneous diphtheria. We did a retrospective analysis of the antimicrobial drug susceptibilities of 46 C. diphtheriae isolates sent during 1993 through 2010 to the French National Reference Centre of Toxigenic Corynebacteria. The isolates came from metropolitan France and French overseas departments and territories. Only 1 isolate, C. diphtheriae biovar mitis,FRC24, expressed the following anti-microbial drug susceptibility profi le: susceptible to penicillin, amoxicillin, cipro. oxacin, clindamycin, erythro-mycin, gentamicin, imipenem, kanamycin, rifampin, tetracycline, and vancomycin and resistant at an uncommonly high level to trimethoprim, sulfamethoxazole, and co-trimoxazole with Etest (bioMérieux, Marcy l'Etoile, France) MICs of >32, >1,024, and >32 mg/L, respectively
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机译：致编者：白喉棒状杆菌是咽和皮肤白喉的制剂。我们对1993年至2010年期间送往法国国家产毒素棒状杆菌参考中心的46株白喉衣原体分离株的抗菌药敏感性进行了回顾性分析。隔离株来自法国大都会以及法国海外部门和地区。仅一种分离株，白喉衣原体生物病毒，FRC24，表达以下抗微生物药敏性：易受青霉素，阿莫西林，环丙沙星的影响。奥沙星，克林霉素，红霉素，庆大霉素，亚胺培南，卡那霉素，利福平，四环素和万古霉素，对甲氧苄氨嘧啶，磺胺甲恶唑和三甲恶唑的抗药性异常高，与Etest（bioMérieux，Marcy EMITES，France） > 32，> 1,024和> 32 mg / L
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