Moxifloxacin Prophylaxis against MDR TB, New York, New York, USA (http://wwwnc.cdc.gov/eid/article/21/3/14-1313)

摘要

Contacts of persons infected with multidrug-resistant tuberculosis (MDR TB) have few prophylaxis options. Of 50 contacts of HIV- and MDR TB–positive persons who were treated with moxifloxacin, 30 completed treatment and 3 discontinued treatment because of gastrointestinal symptoms. Moxifloxacin was generally well-tolerated; further research of its efficacy against MDR TB is needed.