En-face Imaging of Swept-Source Optical Coherence Tomography of Segmental Optic Nerve Hypoplasia.

摘要

Purpose : To observe the retinal nerve fiber bundles (NFB) of segmental optic nerve hypoplasia (SOH) using en-face imaging of swept-source optical coherence tomography (SS-OCT) Methods : 22 eyes from 16 patients with SOH were examined using SS-OCT. Mean age was 40.6?±17.8 yr-old and mean spherical equivalent error was -4.2?±3.0 diopter. Three-dimensional 6 times 6 mm cube raster scans of the optic nerve head and macular were obtained with SS-OCT. The NFB were observed after flatten processing against the inner limiting membrane. Results : In all 22 eyes with SOH, NFB defects were widely distributed from upper to lower nasal around the optic nerve head. The mean angle of NFB defects was 120?±27.1 degrees. No NFB defects were detectable in the macular and lower temporal areas. 6 eyes combined comb-like NFB defects in the upper temporal area. These images were completely different from those with glaucomatous optic neuropathy (GON). Conclusions : Examination of NFB defects by en-face imaging of SS-OCT is quite useful for diagnosis of SOH and for differential diagnosis from GON. This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.