Determination of absolute accuracy of diagnostic tests using bayesian LCMs: A re-evaluation of diagnostic tests for Adenovirus

摘要

Background: Viral culture is considered to be the gold standard method to identify adenoviruses from clinical samples. It can be affected by various factors like transport conditions, pH. As a consequence of this,the accuracy of the different diagnostic tests might have been inaccurately estimated. Objective of this study is evaluating the absolute accuracy of three tests using Bayesian latent class models.