Translating genomics research into control of MDR tuberculosis: Lessons learned and future prospects

摘要

The global MDR-TB caseload is increasingly driven by primary transmission of MDR-TB in high burden countries. Control will require interruption of transmission through earlier detection, effective outbreak investigation, detailed resistance testing to guide tailored treatment for patients with highly resistant TB and development and rapid access to better drugs. Genomics research and the application of technologies enabled through genomic research and technological innovation can play a critical role in each of these areas.