Frequent Detection of HBV and HCV infection in HIV positive cancer patients undergoing chemotherapy or radiotherapy at Dr George Mukhari Academic hospital, Pretoria, South Africa

摘要

Background: Chronic hepatitis, liver cirrhosis and hepatocellular carcinoma by HBV and/or HCV are among the leading causes of death, especially in HIV endemic regions. Though distinct viruses, HBV, HCV and HIV share common routes of transmission, albeit at different efficiency. Chemotherapy and radiotherapy for cancer have been associated with reactivation of viral hepatitis, leading to accelerated hepatitis disease and termination of cancer therapy.