Articles of Significant Interest Selected from This Issue by the Editors

摘要

Iron reduction is a signature of Shewanella oneidensis and this process relies on a large number of cytochromes c, which per se are iron-containing proteins. Thus, iron plays an essential and special role in iron respiration, but it remains largely unexplored. In this study, Fu et al. (e00039-18) have shed light on this topic by probing impacts of Fur, the master regulator of iron homeostasis, on respiration. The loss of Fur causes a general defect in respiration, a result of imbalanced iron homeostasis and dissociation between iron and cytochrome c production.