Forensic DNA Profiling Protocols. Patrick J. Lincoln and Jim Thomson. Totowa, NJ: Humana Press, 1998, 309 pp., $79.50. ISBN 0-896-03443-7.

摘要

Forensic DNA Profiling Protocols is an extensive overview of various methodologies currently used in the forensic-testing community. Some of the topics included are DNA isolation, slot-blot quantification, restriction fragment length polymorphism (RFLP)-Southern blotting, PCR [both dot blot and short tandem repeat (STR) analysis], mitochondrial DNA sequencing, and capillary electrophoresis as well as a review of the statistical evaluation of forensic casework results. The detailed methodologies that are covered follow a retrospective look at DNA techniques as they have evolved since the late 1980s and conclude with a forward-looking chapter on future directions for forensic DNA testing.The first step in DNA profiling is isolating DNA from forensically relevant sources. In …