Phase II study of neoadjuvant imatinib in large gastrointestinal stromal tumours of the stomach

YukinoriKurokawa; Han-KwangYang; HaruhikoCho; Min-HeeRyu; ToruMasuzawa; Sook RyunPark; SoheiMatsumoto; Hyuk-JoonLee; HiroshiHonda; Oh KyoungKwon; TakashiIshikawa; Kyung HeeLee; KazuhitoNabeshima; Seong-HoKong; ToshioShimokawa; Jeong-HwanYook; YuichiroDoki; Seock-AhIm; SeiichiHirota; SeokyungHahn; ToshirouNishida; and Yoon-KooKang

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Phase II study of neoadjuvant imatinib in large gastrointestinal stromal tumours of the stomach

机译：新辅助伊马替尼在胃大胃肠道间质瘤中的II期研究

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Background:Gastrointestinal stromal tumours (GISTs) with high-risk features have poor prognosis even if adjuvant treatment is given. Neoadjuvant imatinib may increase the cure rate by shrinking large GISTs and preserve organ function.

机译：背景：即使给予辅助治疗，具有高危特征的胃肠道间质瘤（GIST）的预后也较差。新辅助伊马替尼可通过收缩大的GISTs来提高治愈率并保留器官功能。

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来源
《British Journal of Cancer》 |2017年第1期|共8页
作者
YukinoriKurokawa; Han-KwangYang; HaruhikoCho; Min-HeeRyu; ToruMasuzawa; Sook RyunPark; SoheiMatsumoto; Hyuk-JoonLee; HiroshiHonda; Oh KyoungKwon; TakashiIshikawa; Kyung HeeLee; KazuhitoNabeshima; Seong-HoKong; ToshioShimokawa; Jeong-HwanYook; YuichiroDoki; Seock-AhIm; SeiichiHirota; SeokyungHahn; ToshirouNishida; and Yoon-KooKang;
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中图分类肿瘤学;
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1. Laparoscopic resection of locally advanced gastrointestinal stromal tumour (GIST) of the stomach following neoadjuvant imatinib chemoreduction [J] . Christophe R. Berney International Journal of Surgery Case Reports . 2015,第12期

机译：新辅助伊马替尼化学还原后腹腔镜切除胃局部晚期胃肠道间质瘤（GIST）
2. Phase II study of dovitinib in patients with metastatic and|[sol]|or unresectable gastrointestinal stromal tumours after failure of imatinib and sunitinib [J] . Y-K Kang, C Yoo, B-Y Ryoo, British Journal of Cancer . 2013,第9期

机译：伊马替尼和舒尼替尼治疗失败后转移性和[或] [或]不可切除的胃肠道间质瘤患者中多维替尼的II期研究
3. Vatalanib for metastatic gastrointestinal stromal tumour (GIST) resistant to imatinib: final results of a phase II study [J] . H Joensuu, F De Braud, G Grignagni, British Journal of Cancer . 2011,第11期

机译：瓦他拉尼治疗对伊马替尼耐药的转移性胃肠道间质瘤（GIST）：II期研究的最终结果
4. Clinical studies of SP1049C, a polymer based anthracycline effective against drug resistant tumors. Results of phase II trial and pivotal phase Ⅲ program in upper gastrointestinal cancer indications [C] . Valery Alakhov Controlled Release Society Annual Meeting and Exposition . 2007

机译：SP1049C的临床研究，一种基于聚合物的蒽环类药物可有效抵抗耐药性肿瘤。上消化道癌适应症的II期试验和关键性III期试验结果
5. Molecular mechanisms of response in gastrointestinal stromal tumors treated with imatinib mesylate [D] . McAuliffe, John Christopher 2007

机译：甲磺酸伊马替尼治疗胃肠道间质瘤的分子机制
6. Phase II study of neoadjuvant imatinib in large gastrointestinal stromal tumours of the stomach [O] . Yukinori Kurokawa, Han-Kwang Yang, Haruhiko Cho, 2017

机译：新辅助伊马替尼在胃大胃肠道间质瘤中的II期研究
7. Laparoscopic resection of locally advanced gastrointestinal stromal tumour (GIST) of the stomach following neoadjuvant imatinib chemoreduction [O] . Christophe R. Berney 2015

机译：新辅助伊马替尼化学减容术后腹腔镜下切除局部晚期胃肠道间质瘤（GIsT）

Phase II study of neoadjuvant imatinib in large gastrointestinal stromal tumours of the stomach

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