Renal and Cardiovascular Effects of sodium?￠??glucose cotransporter 2 (SGLT2) inhibition in combination with loop Diuretics in diabetic patients with Chronic Heart Failure (RECEDE-CHF): protocol for a randomised controlled double-blind cross-over trial

摘要

Abstract Introduction Type 2 diabetes (T2D) and heart failure (HF) are a frequent combination, where treatment options remain limited. There has been increasing interest around the sodium?￠??glucose cotransporter 2 (SGLT2) inhibitors and their use in patie