Systematic literature review and network meta-analysis in highly active relapsing?￠??remitting multiple sclerosis and rapidly evolving severe multiple sclerosis

摘要

Abstract Objective Multiple sclerosis (MS) is a chronic, neurodegenerative autoimmune disorder affecting the central nervous system. Relapsing?￠??remitting MS (RRMS) is the most common clinical form of MS and affects ?￠???85% of cases at onset. Highly active