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Projecting prevalence by stage of care for prostate cancer and estimating future health service needs: protocol for a modelling study

机译:按阶段对前列腺癌的患病率进行预测并估算未来的卫生服务需求:建模研究方案

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Introduction Current strategies for the management of prostate cancer are inadequate in Australia. We will, in this study, estimate current service needs and project the future needs for prostate cancer patients in Australia. Methods and analysis First, we will project the future prevalence of prostate cancer for 2010–2018 using data for 1972–2008 from the New South Wales (NSW) Central Cancer Registry. These projections, based on modelled incidence and survival estimates, will be estimated using PIAMOD (Prevalence, Incidence, Analysis MODel) software. Then the total prevalence will be decomposed into five stages of care: initial care, continued monitoring, recurrence, last year of life and long-term survivor. Finally, data from the NSW Prostate Cancer Care and Outcomes Study, including data on patterns of treatment and associated quality of life, will be used to estimate the type and amount of services that will be needed by prostate cancer patients in each stage of care. In addition, Central Cancer Registry episode data will be used to estimate transition rates from localised or locally advanced prostate cancer to metastatic disease. Medicare and Pharmaceutical Benefits data, linked with Prostate Cancer Care and Outcomes Study data, will be used to complement the Cancer Registry episode data. The methods developed will be applied Australia-wide to obtain national estimates of the future prevalence of prostate cancer for different stages of clinical care. Ethics and dissemination This study was approved by the NSW Population and Health Services Research Ethics Committee. Results of the study will be disseminated widely to different interest groups and organisations through a report, conference presentations and peer-reviewed articles.
机译:引言在澳大利亚,目前用于治疗前列腺癌的策略还不够。在这项研究中,我们将估算当前的服务需求,并预测澳大利亚前列腺癌患者的未来需求。方法和分析首先,我们将使用新南威尔士州(NSW)中央癌症登记处1972-2008年的数据来预测2010-2018年前列腺癌的患病率。这些预测基于建模的发病率和生存率估计值,将使用PIAMOD(患病率,发病率,分析MODel)软件进行估计。然后将总患病率分解为五个阶段的护理:初始护理,持续监测,复发,生命的最后一年和长期幸存者。最后,新南威尔士州前列腺癌护理和结果研究的数据,包括治疗模式和相关生活质量的数据,将用于估计前列腺癌患者在每个护理阶段所需服务的类型和数量。另外,中央癌症登记处的发作数据将用于估计从局部或局部晚期前列腺癌向转移性疾病的转化率。 Medicare和Pharmaceutical Benefits数据与前列腺癌护理和结果研究数据相关,将用于补充Cancer Registry事件数据。所开发的方法将在整个澳大利亚范围内应用,以获取不同阶段临床护理中前列腺癌未来患病率的全国性估计。道德与传播本研究得到新南威尔士州人口与卫生服务研究道德委员会的批准。研究结果将通过报告,会议报告和同行评审文章广泛分发给不同的利益集团和组织。

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