The Pattern of Immunomodulation of ImmuPlus on the Infectious Bursal Disease (IBD) Antibody of Vaccinated Broiler Chickens

摘要

The pattern of immunomodulation of immuplusR on the IBD antibody of vaccinated broiler chicken was investigated in this 70 day study. ImmuplusR, a polyherbal formulation from Ayurved is purported to posses immunomodulatory properties. Ninety nine day old chicks divided into groups A, B, C were used for the study. Two groups, A and B were placed under Immuplus, while group C served as the control. Group A was placed on pulse administration of ImmuPlusR, via drinking water, daily, for 10 days at a 10 day interval from day 8 to day 70. Group B was placed on daily oral administration of ImmuPlusR for the same duration of time. Group C was placed on water only, throughout the experiment. Twelve chickens were bled from each group and the sera harvested for enzyme-linked immunosorbent assay (ELISA) in the evaluation of IBD antibody levels on a weekly basis. The weekly mean values of ELISA results obtained thus were subjected to one-way analysis of variance (ANOVA)and Duncan's multiple range test (DMRT).The treatment groups showed superior antibody response to the control groups for most of the week with significant differences (P<0.05) on the 6th'8th and 10th weeks.The pulse treatment group exhibited inconsistent antibody response. Daily administration was found to enhance their antibody response to gumboro disease and may therefore be useful in its control. It appeared to have a slow onset of action and low residual effect hence the pulse administration of the supplement may not produce a good result.