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首页> 外文期刊>Journal of the Egyptian Society of Cardio-Thoracic Surgery >One-year outcomes of concomitant mitral reduction annuloplasty repair with coronary artery bypass grafting for moderate ischemic mitral regurgitation
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One-year outcomes of concomitant mitral reduction annuloplasty repair with coronary artery bypass grafting for moderate ischemic mitral regurgitation

机译:伴有冠状动脉旁路移植术的二尖瓣减少瓣环成形术修复伴有中度缺血性二尖瓣关闭不全的一年结果

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Background Mitral valve repair for chronic ischemic mitral regurgitation (IMR) in the published literature has contradictory outcomes. Here, we report our center outcomes of reduction annuloplasty technique in addition to myocardial revascularization to treat ischemic IMR over a four-year period. Methods Between January 2011 and December 2014, a total of 40 patients were identified to have a reduced left ventricular ejection fraction who underwent first-time mitral valve reduction annuloplasty concomitantly with coronary artery bypass grafting to treat moderate IMR. Variations in left ventricular end-systolic volume index (LVESVI), left ventricular ejection fraction (LVEF), functional class, and mitral regurgitation (MR) was followed up after surgery and retrospectively analyzed. Results In our cohort, mitral reduction annuloplasty was successful in helping 33 (82%) patients to have no residual MR and to downgrade their MR from moderate (grade 3+) to trace (grade 1+) in 7 (18%) patients before leaving the operating room. A change from baseline value was observed secondary to correction of MR. At 3-months follow-up time; the mean MR grade that was 0.2?±?0.1 by the intraoperative assessment post-bypass has increased significantly to be 1.8?±?0.4 (p??0.05) at early follow-up time, mean LVESVI improved significantly to be 47.6?±?11.0?ml/m 2 , p?
机译:背景技术在已发表的文献中,二尖瓣修复对慢性缺血性二尖瓣关闭不全(IMR)具有矛盾的结果。在这里,我们报告了在四年的时间里,除了进行心肌血运重建以外,还采用了减少瓣环成形术技术的中心成果,以治疗缺血性IMR。方法2011年1月至2014年12月,共40例左心室射血分数降低的患者,他们接受了首次二尖瓣复位瓣膜成形术并冠状动脉搭桥术治疗中度IMR。术后随访左室收缩末期容积指数(LVESVI),左室射血分数(LVEF),功能等级和二尖瓣关闭不全(MR)的变化,并进行回顾性分析。结果在我们的队列中,二尖瓣减少瓣环成形术成功地帮助33例(82%)患者没有残留MR,并将其MR从中等(3+级)降为痕迹(1+级)之前的7名(18%)患者离开手术室。 MR校正后观察到基线值有变化。在三个月的随访时间;术中评估后的平均MR分级为0.2≤±0.1,显着增加至1.8≤±0.4(p≤0.05)。类似地,在手术后一年,与基线值相比,它增加到1.9±±0.3,p <0.05。值得注意的是,我们的患者在术后3个月和1年随访时平均LVEF显着增加(48±1.1%,p <0.05),%(47±4.2%)。 ,p 0.05)与基线值相比(39%±2.3%,两次就诊的p 0.05)。尽管我们的患者在早期随访时平均LVESVI逐渐降低,但无明显下降(57.6?±?9.0?ml / m 2,p?>?0.05),但平均LVESVI显着改善至47.6?±?11.0。 <ml / m 2,一年时p <0.05。在3个月的随访中,LVEF%的这一统计显着增加,除了一年后LVESVI的降低外,还能够引起NYHA功能类别的重大临床变化,这在早期(3个月的随访中)观察到,其中35 (88%)患者成为NYHA I级和II级,后来(手术后1年随访)进入32级(80%)患者仍属于NYHA I级和II级。在一年的随访中没有死亡报告,存活率为95%。在一年的随访期间,由于非心脏疾病,有7例(18%)再次入院。早期手术死亡率(手术后30天内)为5%。一年生存率为95%。平均随访时间为1.1±2.4年(范围1.0-3.5年)。结论伴有手术心肌血运重建的二尖瓣减少瓣膜成形术可能足以纠正中度IMR。它与早期和中期生存率,左心室功能,NYHA分级以及复发性MR的低发生率显着改善有关。

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