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Historical ethnopharmacology of the herbalists from Krummhübel in the Sudety Mountains (seventeenth to nineteenth century), Silesia

机译:西里西亚苏迪底山脉(17至19世纪)克鲁姆胡贝尔的中医师的历史民族药理学

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Krummhübel (after 1945, Karpacz) in the Sudety Mountains (now SW Poland) was called “the village of pharmacists”. At the end of the seventeenth century, there were 57 households, of which about 40 were inhabited by herbalists. Krummhübel herbalists were the first in the Sudety region who applied medicinal mixtures for the treatment of various diseases (using, among others, plants, oils, minerals and even viper venom) in contrast to previous herbalists who only indicated the use of individual plant species for specific diseases. Riesengebirge (in Polish Karkonosze) potions were sold in Austria, the Czech Republic, Poland and Russia, and some of them could even be purchased in Scandinavia and England. The purpose of this paper is an ethnopharmacological analysis of historical texts of herbalists from Krummhübel. Based on their recipes, we analysed the use reports of drugs. Recently, research on ethnobotany and ethnopharmacological analyses of historical materials or egodocuments related to formulations used in folk medicine have become an important source of acquiring knowledge about new medicines. Based on 46 recipes of Krummhübel herbalists re-written by Reitzig (1943), we analysed the use reports of drugs which included plant taxa and other constituents such as animal formulations, fungi, inorganic and organic substances and minerals as well as tinctures (with alcohol/spirit) and elixirs (without alcohol/spirit). For each usage mentioned in the text, we recorded (i) the putative botanical identity of the taxon; (ii) the plant family or origin of other than the plant constituent; (iii) the reported plant part; (iv) the number of the recipe; (v) the name of the recipe; (vi) the vernacular name of ingredient; (vii) the described symptom, ailment or specific use; (viii) our modern (viz. biomedical) interpretation of the described symptom or ailment; (ix) the mode of administration; and (x) the category of use under which we filed the specific use. We also cross-checked the medicinal plants of Krummhübel herbalists with the species described in old manuscripts and regional surveys and compared their use with contemporary plant use. The paper introduces the generated database comprising 348 use reports of 46 drugs based on 70 plant taxa and other constituents. Besides, we address patterns such as the frequent recommendation of Fabaceae herbs for respiratory system issue and gynaecology and Asteraceae for respiratory system and cardiovascular problems. Gastrointestinal use reports are based on Asphodelaceae, Burseraceae and Rosaceae species. Remedies that lost importance over time as well as drugs used for diseases now controlled by conventional medicine may be interesting starting points for research on herbal medicine and drug discovery. It seems to be important to attempt to reproduce therapeutic mixtures from the preserved recipes of Krummhübel herbalists, which offers an opportunity to learn more about the real effects of the former medicines and their therapeutic activity. The obtained data can also be used to search for new drugs.
机译:位于Sudety山(现为波兰西南)的Krummhübel(1945年后为Karpacz)被称为“药剂师之乡”。到17世纪末,这里有57户家庭,其中约40户居住在草药专家的手中。 Krummhübel草药专家是Sudety地区的第一位,他们将药用混合物用于各种疾病的治疗(除其他外,使用植物,油,矿物质甚至毒蛇毒),而以前的草药专家仅指出使用单个植物物种特定疾病。 Riesengebirge(波兰Karkonosze)药水在奥地利,捷克共和国,波兰和俄罗斯出售,其中一些甚至可以在斯堪的纳维亚半岛和英国购买。本文的目的是对克鲁姆胡贝尔的中医历史文献进行民族药理学分析。根据他们的食谱,我们分析了药物的使用报告。近来,对与民间医学中使用的制剂有关的历史材料或自我文献的民族植物学和民族药理学分析的研究已成为获得有关新药知识的重要来源。根据Reitzig(1943年)重写的46种Krummhübel中草药食谱,我们分析了药物的使用报告,其中包括植物类群和其他成分,例如动物配方,真菌,无机和有机物质,矿物质以及tin剂(含酒精) /精神)和长生不老药(不含酒精/精神)。对于本文中提到的每种用法,我们记录(i)分类单元的假定植物学身份; (ii)除植物成分外的植物科或起源; (iii)报告的植物部分; (iv)配方编号; (v)食谱名称; (vi)成分的本地名称; (vii)所描述的症状,疾病或特定用途; (viii)我们对所述症状或不适的现代(即生物医学)解释; (ix)管理方式; (x)我们提交特定用途的用途类别。我们还对Krummhübel中草药的药用植物与旧手稿和区域调查中描述的物种进行了交叉核对,并将它们的用途与当代植物用途进行了比较。本文介绍了所生成的数据库,该数据库包含基于70种植物分类群和其他成分的46种药物的348种使用报告。此外,我们提出了一些模式,例如经常推荐使用豆科植物科植物草药治疗呼吸系统问题和妇科,以及使用菊科来治疗呼吸系统疾病和心血管疾病。胃肠道使用情况的报告是基于水粉科,十字花科和蔷薇科的。随着时间的流逝而失去重要性的补救措施以及目前由常规医学控制的用于疾病的药物可能是草药研究和药物发现的有趣起点。尝试从保存的克鲁姆赫贝尔草药师的食谱中复制治疗混合物似乎很重要,这为了解更多有关前药的实际作用及其治疗活性提供了机会。获得的数据还可以用于搜索新药。

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