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Patient organ doses from megavoltage computed tomography delivery with a helical tomotherapy unit using a general treatment planning system

机译:使用常规的治疗计划系统,通过螺旋断层扫描装置从兆伏计算机断层扫描中输送患者器官剂量

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The purpose of this study was to quantify actual patient organ doses from megavoltage computed tomography (MVCT) using an MVCT beam model of a helical tomotherapy unit in a general treatment planning system (TPS). Dosimetric parameters (percentage depth dose, lateral beam profile, and longitudinal beam profile) of the MVCT beam were measured using Gafchromic EBT3 films (ISP Corporation, Wayne, NJ, USA) and used for beam modeling in a Pinnacle3 TPS (Philips, Amsterdam, Netherlands); this TPS is widely used with linear accelerators. The created beam model was adjusted and validated by assessing point doses in a cylindrical phantom in static and helical beam plans with fine, normal and coarse pitches. Maximum doses delivered to important organs from MVCT delivery for five clinical cases were calculated using the created beam model. The difference (average ± one standard deviation for all evaluation points) between calculated and measured doses was ?0.69 ± 1.20% in the static beam plan. In the helical beam plan, the differences were 1.83 ± 2.65%, 1.35 ± 5.94% and ?0.66 ± 8.48% for fine, normal and coarse pitches, respectively. The average maximum additional dose to important organs from MVCT in clinical cases was 0.82% of the prescribed dose. In conclusion, we investigated a method for quantifying patient organ dose from MVCT delivery on helical tomotherapy using an MVCT beam model in a general TPS. This technique enables estimation of the patient-specific organ dose from MVCT delivery, without the need for additional equipment.
机译:这项研究的目的是在常规治疗计划系统(TPS)中使用螺旋CT的MVCT束模型从兆伏计算机断层扫描(MVCT)量化患者的实际器官剂量。使用Gafchromic EBT3膜(ISP Corporation,Wayne,NJ,USA)测量MVCT光束的剂量参数(百分比深度剂量,横向光束轮廓和纵向光束轮廓),并在Pinnacle3 TPS(Philips,Amsterdam,荷兰);该TPS广泛用于线性加速器。通过评估静态和螺旋光束计划中精细,正常和粗糙间距的圆柱体模型中的点剂量,可以调整和验证创建的光束模型。使用创建的射线束模型,计算了五个临床病例从MVCT输送到重要器官的最大剂量。在静态射线计划中,计算出的剂量与测量出的剂量之间的差异(所有评估点的平均值±平均标准偏差)为±0.69±1.20%。在螺旋光束计划中,细节距,标准节距和粗节距的差异分别为1.83±2.65%,1.35±5.94%和?0.66±8.48%。在临床病例中,MVCT对重要器官的平均最大最大附加剂量为处方剂量的0.82%。总之,我们研究了一种在常规TPS中使用MVCT束模型从螺旋CT上的MVCT输送中量化患者器官剂量的方法。该技术无需额外的设备即可通过MVCT输送来估计患者特定的器官剂量。

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