Critically appraised paper: The addition of exercise training to a weight-loss program improves clinical control in adults with asthma [commentary]

摘要

Question: Does the addition of exercise training to a weight-lossprogram improve asthma control, health-related quality of life, andairway inflammation in obese adults with asthma? Design: Randomised controlled trial with concealed allocation and blinded outcomeassessment. Setting: Tertiary hospital in Brazil. Participants: Inclusion criteria were physically inactive adults (30 to 60 years) withclinically stable moderate/severe asthma and a body mass indexbetween 35 and 40 kg/m2. Exclusion criteria were: cardiovascular,musculoskeletal or other chronic pulmonary disease; uncontrolledhypertension or diabetes; weight changes > 5% and/or antiobesitydrug use within 6 months; bariatric surgery; and (past) smoking.Randomisation of 55 participants allocated 28 to an interventiongroup and 27 to a control group.