Tissue mineral density dependent mechanical properties of individual trabecula plates and rods do not differ in anatomic directions but individual trabecular directions

摘要

Introduction and aims: Trabecular bone, susceptible to osteoporosis, consists of individual trabecular plates and rods, which are distributed distinctlyalong the longitudinal, transverse, or oblique anatomic directions of theskeleton (Fig.1). In each anatomic direction, mechanical properties ofbone tissue are also expected to differ in (axial) or against (lateral) the direction of individual trabeculae, i.e., anisotropic mechanical properties.However, anisotropic mechanical properties of individual trabeculae alongvarious anatomic directions are currently unclear. Objectives of this studywere 1) to measure anisotropic tissue modulus and tissue mineral density(TMD) of individual trabeculae; 2) to examine their dependence on trabecular types and anatomic directions; and 3) to determine the relationship between anisotropic tissue modulus and TMD of individual trabeculae.