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首页> 外文期刊>Journal of Nanobiotechnology >Engineered nanomaterials: toward effective safety management in research laboratories
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Engineered nanomaterials: toward effective safety management in research laboratories

机译:工程纳米材料:致力于研究实验室的有效安全管理

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摘要

It is still unknown which types of nanomaterials and associated doses represent an actual danger to humans and environment. Meanwhile, there is consensus on applying the precautionary principle to these novel materials until more information is available. To deal with the rapid evolution of research, including the fast turnover of collaborators, a user-friendly and easy-to-apply risk assessment tool offering adequate preventive and protective measures has to be provided. Based on new information concerning the hazards of engineered nanomaterials, we improved a previously developed risk assessment tool by following a simple scheme to gain in efficiency. In the first step, using a logical decision tree, one of the three hazard levels, from H1 to H3, is assigned to the nanomaterial. Using a combination of decision trees and matrices, the second step links the hazard with the emission and exposure potential to assign one of the three nanorisk levels (Nano 3 highest risk; Nano 1 lowest risk) to the activity. These operations are repeated at each process step, leading to the laboratory classification. The third step provides detailed preventive and protective measures for the determined level of nanorisk. We developed an adapted simple and intuitive method for nanomaterial risk management in research laboratories. It allows classifying the nanoactivities into three levels, additionally proposing concrete preventive and protective measures and associated actions. This method is a valuable tool for all the participants in nanomaterial safety. The users experience an essential learning opportunity and increase their safety awareness. Laboratory managers have a reliable tool to obtain an overview of the operations involving nanomaterials in their laboratories; this is essential, as they are responsible for the employee safety, but are sometimes unaware of the works performed. Bringing this risk to a three-band scale (like other types of risks such as biological, radiation, chemical, etc.) facilitates the management for occupational health and safety specialists. Institutes and school managers can obtain the necessary information to implement an adequate safety management system. Having an easy-to-use tool enables a dialog between all these partners, whose semantic and priorities in terms of safety are often different.
机译:尚不清楚哪种类型的纳米材料及其相关剂量对人类和环境构成实际威胁。同时,在将预防性原则应用于这些新颖材料上达成共识,直到获得更多信息为止。为了应对研究的快速发展,包括合作者的快速周转,必须提供易于使用且易于使用的风险评估工具,该工具应提供足够的预防和保护措施。基于有关工程纳米材料危害的新信息,我们遵循简单的方案来提高效率,从而改进了先前开发的风险评估工具。第一步,使用逻辑决策树,将从H1到H3的三个危害级别之一分配给纳米材料。使用决策树和矩阵的组合,第二步将危害与排放和暴露潜力联系起来,以将三种纳米风险级别之一(纳米3最高风险;纳米1最低风险)分配给活动。在每个过程步骤中重复这些操作,从而导致实验室分类。第三步为确定的纳米风险水平提供了详细的预防和保护措施。我们为研究实验室开发了一种适用于纳米材料风险管理的简单而直观的方法。它可以将纳米活性分为三个级别,另外还提出了具体的预防和保护措施以及相关措施。对于所有纳米材料安全参与者而言,该方法都是一种有价值的工具。用户将体验基本的学习机会,并提高他们的安全意识。实验室管理人员拥有可靠的工具,可以概览实验室中涉及纳米材料的操作。这是必不可少的,因为他们负责员工的安全,但有时不知道所执行的工作。将此风险扩大到三级范围(就像其他类型的风险,如生物,辐射,化学等),有助于职业健康和安全专家的管理。机构和学校管理者可以获取必要的信息,以实施适当的安全管理体系。拥有易于使用的工具可以在所有这些合作伙伴之间进行对话,这些合作伙伴的语义和安全重点通常是不同的。

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