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Human Exposure Assessment of Element Pollution for Environmental Health Implications: Teeth as a Biomonitoring Tool

机译:人体对元素污染的暴露评估对环境健康的影响:牙齿作为生物监测工具

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Reference values reflecting the findings of natural concentrations of teeth in a well-defined group of individuals, are indispensable, if one is to interpret results generated for clinical utility. Hence, a comprehensive compilation of literature survey is attempted to make available as a reference guideline for tooth element concentrations. Presently, the reference values are proposed for 19 elements. Several factors that are found influencing element levels, are common to any biosample and are broadly grouped under four categories namely, the factors of teeth, donor, environment and analytical methods. How best the influencing factors to be considered during analysis, are discussed. It is elucidated that standardized method of analysis with quality assurance and precision will reduce the ambiguity of comparison of inter-laboratory measurement. When the merits and demerits of element measurements are evaluated, it is recognized that except a hurdle of difficult specific sampling, many advantages make teeth an attractive material for environmental health monitoring of population and for assessment of element status of deficiency and excess due to differential exposure. The available data of tooth elements are lesser in comparison to data of blood and hair; further studies are required for reference values of others elements and for distribution pattern in different conditions, parts and types of teeth.
机译:如果要解释为临床效用而产生的结果,则反映必不可少的参考值必不可少。因此,试图对文献调查进行全面的整理,以作为牙齿元素浓度的参考指南。目前,建议为19个元素提供参考值。已发现影响元素水平的几个因素是任何生物样品共有的,并且大致分为四类,即牙齿,供体,环境和分析方法等因素。讨论了如何在分析过程中最好地考虑影响因素。阐明了具有质量保证和准确性的标准化分析方法将减少实验室间测量的比较的歧义。在评估元素测量的优缺点时,人们认识到,除了困难的特定采样障碍外,许多优点使牙齿成为有吸引力的材料,可用于监视人群的环境健康以及评估由于差异暴露而引起的元素不足和过量的元素状态。与血液和头发的数据相比,牙齿元素的可用数据要少。对于其他元素的参考值以及在不同条件,部位和类型的牙齿上的分布方式,还需要进一步研究。

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