Study on the correlation of carotid IMT with Hcy, Cyst-C, UA, and Lp(a) in middle-aged patients with H-type hypertension

摘要

Objective: To explore the correlation of carotid IMT (cIMT) with Hcy, Cyst-C, UA, and Lp(a)in middle-aged patients with H-type hypertension. Methods: A total of 120 middle-agedpatients with H-type hypertension who were admitted in our hospital from July, 2015 to July,2016 were included in the study. The color Doppler ultrasound diagnostic apparatus was usedfor the two-dimensional ultrasound examination. The patients were divided into the normalgroup, thickening group, and plaque group with 40 cases in each group according to theatherosclerosis (AS). The full automatic biochemical analyzer was used to detect the plasmaHcy, Cyst-C, UA, Scr, Bun, TC, TG, LDL-C, and HDL-C. Emulsion turbidity method wasused to detect Lp(a). Results: With the thickening of cIMT, Hcy, Cyst-C, Lp(a), and UA levelswere elevated, while HDL-C level was reduced. Conclusions: The serum Hcy, Cyst-C, UA,and Lp(a) levels in middle-aged patients with H-type hypertension are positively correlatedwith cIMT, are the independent risk factors for developing AS, and can be served as the earlyindicators to estimate the occurrence and development of AS.