首页> 外文期刊>Journal of Cosmetics, Dermatological Sciences and Applications >Targetoid Polycyclic Concentric Hair Regrowth Pattern Is a Sign of Immunological Recovery in Alopecia Areata
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Targetoid Polycyclic Concentric Hair Regrowth Pattern Is a Sign of Immunological Recovery in Alopecia Areata

机译:Targetoid多环同心头发再生模式是脱发区域免疫恢复的标志。

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Background : Alopecia areata is a common autoimmune disease, where there are many topical and systemic therapies, during which hair growth appears in a uniform pattern. In certain cases, hair regrowth takes a polycyclic pattern simulating a target, so called targetoid phenomena. Objective: To screen all cases of treated alopecia areata for hair targetoid regrowth pattern. ? Methods: This is an observational study, was conducted in Dermatology Department of Baghdad Teaching Hospital in Iraq, during the period, August 2017 to October 2017 . All cases treated for alopecia areata with IM triamcinolone 20 - 40 mg injection every 2 weeks with topical clobetasone ointment and zinc sulfate 2 mg/kg/day for 2 months, were examined for the targetoid concentric hair regrowth pattern. Result: Among all cases of alopecia areata, seven patients were recorded to have the targetoid concentric hair pattern, which seen 2 - 4 weeks after therapy, their ages ranged from 4 to 25 years old with a mean 14.5, all of them were males. All these patients returned back with hair growth in a form of rings of hair growth alternating with rings of little or no hair growth forming a typical picture of target. Conclusion: Targetoid polycyclic concentric hair regrowth pattern is an important phenomenon seen in patients receiving treatment for alopecia areata, which is a good sign of recovery where its etiopathogenesis could not well be elucidated but alternating immunological reactions could explain this targetoid pattern.
机译:背景:斑秃是一种常见的自身免疫性疾病,其中有许多局部和全身疗法,其间毛发生长均匀。在某些情况下,头发的再生长采用多环模式来模拟目标,即所谓的目标样现象。 目的:筛选所有经治疗的斑秃区域的头发目标样物再生长模式。 ? 方法:这是一项观察性研究,于2017年8月至2017年10月在伊拉克巴格达教学医院皮肤科进行。每2周用IM曲安西龙注射20-40 mg,局部用氯倍他松软膏和硫酸锌2 mg / kg /天治疗2个月,治疗斑秃的所有病例,检查其目标样同心发长的规律。 结果:在所有斑秃患者中,有7名患者出现了目标样的同心发型,在治疗后2-4周内发现,他们的年龄在4至25岁之间,平均年龄为14.5,所有这些患者是男性。所有这些患者以毛发生长环的形式与毛发生少或没有毛发生长的环交替出现的毛发生长返回,从而形成典型的目标图片。 结论:类固醇多环同心毛再生长模式是接受斑秃治疗的患者中的一种重要现象,这是恢复的好兆头,其病因无法很好地阐明,但交替的免疫反应可以解释该类固醇模式。

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