A Review on Study of Hepatoprotective Activity of Chenopodium Album Linnon CCl4 Induced Hepatotoxicity in Rats

摘要

The hepatoprotective activity of Chenopodium album Linn leaves against carbon tetrachloride (CCl4)-induced hepatotoxicity was investigated. Possibilities of Rat hepatocyte monolayer culture and rats were used as in vitro and in vivo hepatoprotective screening models also very useful. In the in vitro studies, different extracts and fraction we can screened. Silymarin can be used as reference drug. In the in vivo studies, hepatotoxicity was induced in wistar rats species give satisfactory results as per reported methods and administering a mixture of CClsub4/sub: olive oil (1:1, 2 ml/kg, s.c.) can be used for the inducible purpose. The extent of hepatotoxicity can be assessed by measuring the serum enzyme levels. So overall parameters consider for the CClsub4 /subinduced hapatoxicity in rats.