Assessment of Impaired Fasting Glucose in Obese and Overweight Insulin-Resistant Children by Continuous Glucose Monitoring

摘要

T he childhood obesity epidemic has been accompanied by an increase in the prevalence of type 2 diabetes mellitus, with impaired glucose tolerance (IGT) reported in 10–27% of obese children and adolescents across the globe. 1,2 The natural history of impaired fasting glucose (IFG) and IGT is variable, with ~25% progressing to diabetes, 50% remaining in their abnormal glycemic state, and 25% reverting to normal glucose tolerance over an observational period of 3–5 years. 3