“Revised diagnostic criteria” for Vogt-Koyanagi-Harada disease fail to improve disease management

摘要

Vo g teKoyanagieHarada (VKH) disease is a bilateral,chronic granulomatous panuveitis associated with centralnervous system, auditory, and integumentary manifestations.Classically, the disease begins with a prodromal phase ofneuroauditory symptoms, followed by an acute uveitis phase,and finally, the chronic stage manifestations. However, it isnot uncommon for patients with initial-onset VKH disease topresent with the isolated ocular disease, without associatedneuroauditory symptoms.1Any delay in establishing thecorrect diagnosis of initial-onset VKH disease and in initiating adequate treatment may result in higher risks ofchronicity, complications, and visual impairment.2,3Therefore, accurate recognition of the distinctive ocular featuresassociated with the initial-onset VKH will help to establishan early definitive diagnosis, with prompt initiation ofappropriate treatment.