Sulfamic acid as energy efficient catalyst for synthesis of flurophores, 1-e???-spiro [isoindoline-1,2a€2-quinazoline]-3,4a€2(3a€2e???)-diones

摘要

An energy efficient synthesis of 1-e???-spiro[isoindoline-1,2a€2-quinazoline]-3,4a€2(3a€2e???)-diones has been expediently accomplished by a reaction of isatin(s) / cyclic ketone and anthranilamide in ethanol at ambient temprature. Excellent yields of the products in short time duration, operational simplicity, and simple work-up procedure are the attractive features of the present protocol. Synthesized 1-e???-spiro[isoindoline-1,2a€2-quinazoline]-3,4a€2(3a€2e???)-diones were found to be fluorescent with absorption in UV region (302, 362 nm) and emission in visible region (413-436 nm) with Stokes shift of 44-72 nm.