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Adductor focal laryngeal Dystonia: correlation between clinicians’ ratings and subjects’ perception of Dysphonia

机译:收治者局灶性喉肌张力障碍:临床医生的评分与受试者对声调障碍的认识之间的相关性

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Background Although considerable research has focused on the etiology and symptomology of adductor focal laryngeal dystonia (AD-FLD), little is known about the correlation between clinicians’ ratings and patients’ perception of this voice disturbance. This study has five objectives: first, to determine if there is a relationship between subjects’ symptom-severity and its impact on their quality of life; to compare clinicians’ ratings with subjects’ perception of the individual characteristics and severity of AD-FLD; to document the subjects’ perception of changes in dysphonia since diagnosis; to record the frequency of voice arrest during connected speech; and, finally, to calculate inter-clinician reliability based on results from the Unified Spasmodic Dysphonia Rating Scale (USDRS) (Stewart et al, J Voice 1195-10, 1997). Methods Sixty subjects with AD-FLD who were receiving ongoing injections of BoNT participated in this study. Subjects’ mean age was 60.78?years and their mean duration of symptoms was 16.1?years. Subjects completed the Disease Symptom Questionnaire (DSQ) (specifically designed for this study) and the Voice Handicap Index-10 (VHI-10) (Jacobson et al, Am J Speech Lang Pathol 6:66–70, 1997) to measure the symptoms of their dysphonia and the impact of the disease on their quality of life. Two speech-language pathologists and two laryngologists used the Voice Arrest Measure (VAM) (specifically designed for this study) and the USDRS to independently rate voice recordings of 56/60 subjects. Results The mean VHI-10 score was 21.3 which is clinically significant. The results of the DSQ and the USDRS were highly correlated. The most severe symptoms identified by both subjects and clinicians were roughness, strain-strangled voice quality, and increased expiratory effort. Voice arrest, aphonia, and tremor were uncommon. Subjects rated their current voice quality at the time of reinjection (i.e., at the time of the study) as significantly better than at the time of their initial AD-FLD diagnosis ( p
机译:背景技术尽管大量研究集中于内收肌局灶性肌张力障碍(AD-FLD)的病因和症状,但对临床医师的评分与患者对该声音障碍的感知之间的相关性知之甚少。这项研究有五个目标:首先,确定受试者的症状严重程度与其对生活质量的影响之间是否存在关联;比较临床医生的评分与受试者对AD-FLD的个体特征和严重程度的看法;记录受试者自诊断以来对声调变化的感知;记录语音在连接语音中的频率;最后,根据统一痉挛性听音障碍评定量表(USDRS)的结果来计算临床医生之间的可靠性(Stewart等人,J Voice 1195-10,1997)。方法接受BoNT持续注射的60名AD-FLD受试者参加了本研究。受试者的平均年龄为60.78岁,平均症状持续时间为16.1岁。受试者完成了疾病症状问卷(DSQ)(专门为该研究设计)和语音障碍指数10(VHI-10)(Jacobson等人,Am J Speech Lang Pathol 6:66-70,1997)以测量症状的发声困难以及疾病对生活质量的影响。两名语言病理学家和两名喉头科医生使用了“声音逮捕措施”(VAM)(专门为此研究设计)和USDRS,分别对56/60名受试者的声音记录进行评分。结果VHI-10平均得分为21.3,具有临床意义。 DSQ和USDRS的结果高度相关。受试者和临床医生均识别出的最严重症状是粗糙,勒死勒索的语音质量和呼气强度增加。声音骤停,失音和震颤很少见。受试者对他们在回注时(即研究时)的当前语音质量的评价明显好于其最初的AD-FLD诊断时(p <0.0001)。 USDRS的跨临床医生可靠性在0.001水平上很显着。结论VHI-10的发现表明AD-FLD对生活质量有深远的影响。 DSQ和USDRS的结果表明,受试者的知觉与临床医生对个体症状和声音障碍严重程度的评估之间存在很强的相关性。 VAM的发现表明,接受持续BoNT注射的AD-FLD患者很少发生声音骤停。 USDRS的强大的跨临床医生可靠性表明,这是识别AD-FLD症状和严重程度的适当措施。

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