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Chronological Improvement in Survival of Patients with Breast Cancer: A Large-Scale, Single-Center Study

机译:按时间顺序改善乳腺癌患者生存率的大型单中心研究

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Purpose This study aimed to chronologically evaluate survival of patients with breast cancer in Korea and investigate the observed changes during the last 20 years. We also sought to determine factors that may influence outcomes and changes in the duration of survival over time. Methods We retrospectively analyzed a total of 10,988 patients with breast cancer who were treated at our institution between January 1993 and December 2008. We divided the study period into three periods (P1, 1993–1997; P2, 1998–2002; and P3, 2003–2008). We retrospectively reviewed the collected data from the Asan database, including age at diagnosis, clinical manifestations, pathology report, surgical methods, types of adjuvant treatment modalities, type of recurrence, and follow-up period. Results At a median follow-up of 8.2 years, we observed that survival outcomes have improved recently. The 5-year breast cancer-specific survival (BCSS) rate also increased from 82.8% in P1 to 92.6% in P3 ( p Conclusion The study results suggest an improvement in breast cancer survival in Korea, which is consistent with the development of treatments and early detection.
机译:目的这项研究旨在按时间顺序评估韩国乳腺癌患者的生存率,并调查过去20年间观察到的变化。我们还试图确定可能影响结果和生存时间随时间变化的因素。方法我们回顾性分析了1993年1月至2008年12月间在本院接受治疗的10988例乳腺癌患者。我们将研究期分为三个阶段(P1,1993-1997; P2,1998-2002; P3,2003)。 –2008年)。我们回顾性地回顾了从Asan数据库中收集的数据,包括诊断时的年龄,临床表现,病理报告,手术方法,辅助治疗方式的类型,复发的类型以及随访时间。结果在平均8.2年的随访中,我们观察到生存结局最近有所改善。 5年乳腺癌特异性生存率(BCSS)也从P1的82.8%上升至P3的92.6%(p结论研究结果表明,韩国的乳腺癌生存率有所提高,这与治疗方法的发展相一致。早期发现。

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