Effect of including historical height and radius BMD measurement on sarco-osteoporosis prevalence

摘要

BackgroundA clinical need exists to improve identification of those who will sustain fragility fractures. Individuals with both osteoporosis (OP) and sarcopenia (SP), so-called “sarco-osteoporosis” (SOP), might be at higher fracture risk than those with OP or SP alone. Approaches to facilitate SOP identification, e.g., use of tallest historical rather than current height and inclusion of radius bone mineral density (BMD) measurement, may be of benefit. This study examined the effect of advancing age on SOP prevalence with and without use of historical tallest height and radius BMD measurement.MethodsAdults age 60+ underwent dual-energy X-ray absorptiometry (DXA) BMD and total body composition measurement. OP and SP were defined using standard criteria: T-score ≤?2.5 at the lumbar spine or hip and appendicular lean mass (ALM)/current height2 <5.45?kg/m2 (female) and <7.26?kg/m2 (male). Proposed “sensitive” SP criteria used historical tallest height instead of current height, while “sensitive” OP criteria added the 1/3rd radius T-score. The primary outcome was SOP prevalence by decade (60–69, 70–79, 80+).ResultsA total of 304 individuals (146?M/158?F) participated. OP, SP and SOP prevalence were higher in older adults and increased (p?