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Optimizing the MLC model parameters for IMRT in the RayStation treatment planning system

机译:在RayStation治疗计划系统中为IMRT优化MLC模型参数

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Unlike other commercial treatment planning systems (TPS) which model the rounded leaf end differently (such as the MLC dosimetric leaf gap (DLG) or rounded leaf-tip radius), the RayStation TPS (RaySearch Laboratories, Stockholm, Sweden) models transmission through the rounded leaf end of the MLC with a step function, in which the radiation transmission through the leaf end is the square root of the average MLC transmission factor. We report on the optimization of MLC model parameters for the RayStation planning system. This (TPS) models the rounded leaf end of the MLC with the following parameters: leaf-tip offset, leaf-tip width, average transmission factor, and tongue and groove. We optimized the MLC model parameters for IMRT in the RayStation v. 4.0 planning system and for a Varian C-series linac with a 120-leaf Millennium MLC, and validated the model using measured data. The leaf-tip offset is the geometric offset due to the rounded leaf-end design and resulting divergence of the light/radiation field. The offset value is a function of the leaf-tip position, and tabulated data are available from the vendor. The leaf-tip width was iteratively evaluated by comparing computed and measured transverse dose profiles of MLC defined fields at d max in water. In-water profile comparisons were also used to verify the MLC leaf position (leaf-tip offset). The average transmission factor and leaf tongue-and-groove width were derived iteratively by maximizing the agreement between measurements and RayStation TPS calculations for five clinical IMRT QA plans. Plan verifications were performed by comparing MapCHECK2 measurements and Monte Carlo calculations. The MLC model was validated using five test IMRT cases from the AAPM Task Group 119 report. Absolute gamma analyses ( 3 mm / 3 % and 2 mm / 2 % ) were applied. In addition, computed output factors for MLC-defined small fields ( 2 × 2 , 3 × 3 , 4 × 4 , 6 × 6 cm 2 ) of both 6 MV and 18 MV photons were compared to those independently measured by the Imaging and Radiation Oncology Core (IROC), Houston, TX. 6 MV and 18 MV models were both determined to have the same MLC parameters: leaf-tip offset = 0.3 cm , 2.5 % transmission, and leaf tongue-and-groove width = 0.05 cm . IMRT QA analysis for five test cases in TG-119 resulted in a 100% passing rate with 3 mm / 3 % gamma analysis for 6 MV, and > 97.5 % for 18 MV. The passing rate was > 94.6 % for 6 MV and > 90.9 % for 18 MV when the 2 mm / 2 % gamma analysis criteria was applied. These results compared favorably with those published in AAPM Task Group 119. The reported MLC model parameters serve as a reference for other users.PACS number(s): 87.55.D, 87.56.nk
机译:与其他商业化处理计划系统(TPS)对圆角末梢进行不同建模(例如MLC剂量叶间隙(DLG)或圆角末梢半径)不同,RayStation TPS(RaySearch Laboratories,斯德哥尔摩,瑞典)对通过具有阶跃函数的MLC的圆形叶端,其中穿过叶端的辐射透射率是平均MLC透射因子的平方根。我们报告了RayStation计划系统的MLC模型参数的优化。此(TPS)使用以下参数对MLC的圆形叶端建模:叶尖偏移,叶尖宽度,平均透射系数以及舌和沟。我们优化了RayStation v.4.0计划系统中IMRT的MLC模型参数,以及带有120叶Millennium MLC的Varian C系列直线加速器的MLC模型参数,并使用测量数据验证了模型。叶尖偏移量是由于圆形末端设计而导致的光/辐射场的发散所导致的几何偏移量。偏移值是叶尖位置的函数,可以从供应商处获得列表数据。通过比较水中d max处MLC定义的场的计算和测量的横向剂量分布曲线来迭代评估叶尖宽度。在水中的轮廓比较还用于验证MLC叶片位置(叶尖偏移)。通过最大化五个IMRT QA计划的测量值与RayStation TPS计算之间的一致性,迭代地得出平均透射因子和叶舌根与凹槽的宽度。通过比较MapCHECK2测量值和蒙特卡洛计算来执行计划验证。使用AAPM任务组119报告中的五个IMRT测试案例对MLC模型进行了验证。进行了绝对伽马分析(3 mm / 3%和2 mm / 2%)。此外,将6 MV和18 MV光子的MLC定义的小视场(2×2、3×3、4×4、6×6 cm 2)的计算输出因子与通过成像和辐射独立测量的输出因子进行了比较。肿瘤核心(IROC),德克萨斯州休斯敦。确定6个MV和18个MV模型均具有相同的MLC参数:叶尖偏移= 0.3 cm,透射率为2.5%,叶舌槽宽度= 0.05 cm。对TG-119中的五个测试用例进行IMRT QA分析可得出100%的通过率,其中6 MV的3 mm / 3%伽马分析,18 MV的> 97.5%。当使用2 mm / 2%的伽马分析标准时,通过率对于6 MV为> 94.6%,对于18 MV为> 90.9%。这些结果与AAPM任务组119中发布的结果相比具有优势。所报告的MLC模型参数可为其他用户提供参考。PACS编号:87.55.D,87.56.nk

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