首页> 外文期刊>Journal for ImmunoTherapy of Cancer >Anti-PD-1 mAb pre-radiotherapy (RT) loading dose and fractionated RT induce better tumor-specific immunity and tumor shrinkage than sequential administration in an HPV+ head and neck cancer model

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Anti-PD-1 mAb pre-radiotherapy (RT) loading dose and fractionated RT induce better tumor-specific immunity and tumor shrinkage than sequential administration in an HPV+ head and neck cancer model

机译：在HPV +头颈癌模型中，抗PD-1 mAb预放射治疗（RT）负荷剂量和分次RT诱导比顺序给药更好的肿瘤特异性免疫和肿瘤缩小

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来源
《Journal for ImmunoTherapy of Cancer》 |2015年第s2期|共页
作者
Raghvendra M Srivastava; David A Clump; Robert L Ferris;
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中图分类肿瘤学;
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1. Treatment-naive HPV+ head and neck cancers display a T-cell-inflamed phenotype distinct from their HPV- counterparts that has implications for immunotherapy [J] . Steven F. Gameiro, Farhad Ghasemi, John W. Barrett, Oncoimmunology. . 2018,第10期

机译：治疗 - 幼稚HPV +头部和颈部癌症显示出与其HPV-对应物不同的T细胞发炎的表型，其具有对免疫疗法的影响
2. Targeting EZH2 Enhances Antigen Presentation, Antitumor Immunity, and Circumvents Anti-PD-1 Resistance in Head and Neck Cancer [J] . Zhou Liye, Mudianto Tenny, Ma Xiaojing, Clinical cancer research: an official journal of the American Association for Cancer Research . 2020,第1期

机译：靶向EZH2增强抗原呈递，抗肿瘤免疫力，并避免头部和颈部癌症的抗PD-1抗性
3. Enhanced local dendritic cell activity and tumor-specific immunoresponse in combined radiofrequency ablation and interleukin-2 for the treatment of human head and neck cancer in a murine orthotopic model. [J] . Saito K, Araki K, Reddy N, Head and neck: Journal for the sciences and specialities of the head and neck . 2011,第3期

机译：联合射频消融和白细胞介素2可以增强局部树突状细胞的活性和肿瘤特异性免疫反应，从而在鼠原位模型中治疗人的头颈癌。
4. Anti-PD-1 mAb pre-radiotherapy (RT) loading dose and fractionated RT induce better tumor-specific immunity and tumor shrinkage than sequential administration in an HPV+ head and neck cancer model [O] . Raghvendra M Srivastava, David A Clump, Robert L Ferris 2015

机译：在HPV +头颈癌模型中抗PD-1 mAb放射治疗前（RT）负荷剂量和分次RT诱导比顺序给药更好的肿瘤特异性免疫和肿瘤缩小
5. Anti-PD-1 mAb pre-radiotherapy (RT) loading dose and fractionated RT induce better tumor-specific immunity and tumor shrinkage than sequential administration in an HPV+ head and neck cancer model [O] . 2015

机译：在HPV +头颈癌模型中，抗PD-1 mAb放射治疗前（RT）负荷剂量和分次RT诱导比顺序给药更好的肿瘤特异性免疫和肿瘤缩小

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