Intravenous injection of a modified vaccinia ankara virus induces intratumoral CD8+ lymphocyte infiltration favoring tumor control in an orthotopic tumor model upon combinatorial treatment with a TLR9 agonist

Laetitia Fend; Tanja Gatard-Scheikl; Jacqueline Kintz; Murielle Gantzer; Emmanuelle Schaedler; Karola Rittner; Sandrine Cochin; Sylvie Fournel; Xavier Préville

首页> 外文期刊>Journal for ImmunoTherapy of Cancer >Intravenous injection of a modified vaccinia ankara virus induces intratumoral CD8+ lymphocyte infiltration favoring tumor control in an orthotopic tumor model upon combinatorial treatment with a TLR9 agonist

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Intravenous injection of a modified vaccinia ankara virus induces intratumoral CD8+ lymphocyte infiltration favoring tumor control in an orthotopic tumor model upon combinatorial treatment with a TLR9 agonist

机译：经TLR9激动剂联合治疗后，静脉注射修饰的牛痘安卡拉病毒可诱导肿瘤内CD8 +淋巴细胞浸润，从而促进原位肿瘤模型中的肿瘤控制。

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来源
《Journal for ImmunoTherapy of Cancer》 |2014年第s3期|共页
作者
Laetitia Fend; Tanja Gatard-Scheikl; Jacqueline Kintz; Murielle Gantzer; Emmanuelle Schaedler; Karola Rittner; Sandrine Cochin; Sylvie Fournel; Xavier Préville;
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中图分类肿瘤学;
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1. Intravenous Injection of MVA Virus Targets CD8+ Lymphocytes to Tumors to Control Tumor Growth upon Combinatorial Treatment with a TLR9 Agonist [J] . Laetitia Fend, Tanja Gatard-Scheikl, Jacqueline Kintz, Cancer immunity . 2014,第12期

机译：静脉注射MVA病毒可将CD8 +淋巴细胞靶向肿瘤，以控制TLR9激动剂联合治疗后肿瘤的生长。
2. The combination of intratumoral delivery of inactivated modified vaccinia virus Ankara with systemic delivery of immune checkpoint blockade enhances antitumor immunity [J] . Wang W., Dai P., Yang N., The Journal of investigative dermatology. . 2018,第5a19期

机译：灭活改性痘苗病毒ankara的肿瘤内递送的组合具有免疫检查点梗死的全身递送增强了抗肿瘤免疫力
3. Combination of Intratumoral injections of vaccinia virus MVA expressing GM-CSF and immunization with DNA vaccine prolongs the survival of mice bearing HPV16 induced tumors with downregulated expression of MHC class I molecules. [J] . Nemeckova S, Smahel M, Hainz P, Neoplasma: Journal of Experimental and Clinical Oncology . 2007,第4期

机译：瘤内注射表达GM-CSF的牛痘病毒MVA并用DNA疫苗免疫可延长带有HPV16诱导肿瘤且MHC I类分子表达下调的小鼠的存活。
4. Intravenous injection of a modified vaccinia ankara virus induces intratumoral CD8+ lymphocyte infiltration favoring tumor control in an orthotopic tumor model upon combinatorial treatment with a TLR9 agonist [O] . Laetitia Fend, Tanja Gatard-Scheikl, Jacqueline Kintz, 2014

机译：经TLR9激动剂联合治疗后静脉注射改良牛痘安卡拉病毒可诱导肿瘤内CD8 +淋巴细胞浸润从而促进原位肿瘤模型中的肿瘤控制。
5. Intravenous injection of a modified vaccinia ankara virus induces intratumoral CD8+ lymphocyte infiltration favoring tumor control in an orthotopic tumor model upon combinatorial treatment with a TLR9 agonist [O] . 2014

机译：经TLR9激动剂联合治疗后，静脉注射改良牛痘安卡拉病毒可诱导肿瘤内CD8 +淋巴细胞浸润，从而促进原位肿瘤模型中的肿瘤控制。

Intravenous injection of a modified vaccinia ankara virus induces intratumoral CD8+ lymphocyte infiltration favoring tumor control in an orthotopic tumor model upon combinatorial treatment with a TLR9 agonist

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