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首页> 外文期刊>Japanese Journal of Pharmacology >ENHANCEMENT OF NADPH-DEPENDENT LIPID PEROXIDATION ACTIVITY BY ETHYLENE-DIAMINETETRAACETIC ACID (EDTA) IN THE PRESENCE OF FERROUS ION IN RABBIT LIVER MICROSOMES
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ENHANCEMENT OF NADPH-DEPENDENT LIPID PEROXIDATION ACTIVITY BY ETHYLENE-DIAMINETETRAACETIC ACID (EDTA) IN THE PRESENCE OF FERROUS ION IN RABBIT LIVER MICROSOMES

机译:乙烯-肝微粒体中亚铁离子存在下乙烯-二胺基乙酸(EDTA)增强依赖于NADPH的脂质过氧化活性

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References(9) Cited-By(7) The addition of EDTA to the incubation mixture containing rabbit liver microsomes and ferrous ion resulted in 2-fold increase of lipid peroxidation activity. Such an enhancement was not observed in rat liver microsomes. The maximum lipid peroxidation activity seen in rabbit microsomes in the presence of EDTA and ferrous ion was about 80% that seen in rat liver microsomes. From these results, it is likely that low lipid peroxidation activity in rabbit liver microsomes may account for the insufficiency of an EDTA-like factor(s) in rabbit liver microsomes.
机译:参考文献(9)引用(7)在含有兔肝微粒体和亚铁离子的培养混合物中添加EDTA可使脂质过氧化活性增加2倍。在大鼠肝微粒体中未观察到这种增强。在EDTA和亚铁离子存在下,兔微粒体中可见的最大脂质过氧化活性约为大鼠肝脏微粒体中的80%。从这些结果来看,兔肝微粒体中的脂质过氧化活性低可能解释了兔肝微粒体中EDTA样因子不足的原因。

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