...
首页> 外文期刊>Dynamic Chiropractic >Research on herbal combinations of traditional Chinese medicine for chronic gastritis based on network biology
【24h】

Research on herbal combinations of traditional Chinese medicine for chronic gastritis based on network biology

机译:基于网络生物学的慢性胃炎中药复方研究

获取原文
           

摘要

Herbal combinations are important for traditional Chinese medicine physicians to treat diseases. Based on Professor GAO Zhongying’s medical records, combination laws are explored in order to study and inherit Professor GAO’s academic thoughts and improve the level of clinical treatment from multiple perspectives in treating chronic gastritis. Based on an entropy clustering method of complex systems, Professor GAO’s formula data is mined to draw the combinations which have good effects on the treatment of chronic gastritis. Meanwhile, the software Pajek developed for complex network was applied in the process. It not only provides a group of fast and efficient algorithms to analyze complex networks, but also presents a visual interface to facilitate the understanding on the structural characteristics of complex networks from a visual point of view. Through analyzing the commonness of Professor GAO’s formulas, we found the compatibility structure that reflected formula thinking and core clinical features, and supported the arrangement of Professor GAO’s experiences. Through the procedure mentioned mentioned, we analyzed and screened 730 formulas in the database, and found 30 herbs most frequently used in the treatment of chronic gastritis. By applying the measure of modified mutual information, we got 94 commonly-used herbs with correlation coefficients above 0.05; and through the entropy clustering method of complex systems, we found 11 core combinations. The entropy clustering method of complex systems was used to build the association among 80 herbs commonly used to treat chronic gastritis, and then 122 associations were obtained. We draw out the complex network graph of herbs commonly used for chronic gastritis. These results are completely in line with clinical practices, and they are essentially the commonly used herbs employed by Professor GAO Zhongying for chronic gastritis.
机译:草药组合对于中医治疗疾病非常重要。以高中英教授的病历为基础,探索结合法,以研究和继承高教授的学术思想,从多角度提高慢性胃炎的临床治疗水平。基于复杂系统的熵聚类方法,GAO教授的公式数据被提取出来,以得出对慢性胃炎的治疗效果良好的组合。同时,在此过程中使用了为复杂网络开发的Pajek软件。它不仅提供了一组快速有效的算法来分析复杂网络,而且还提供了可视界面,以帮助从视觉角度理解复杂网络的结构特征。通过分析GAO教授配方的共同点,我们发现了反映配方思维和核心临床特征的相容性结构,并支持GAO教授经验的安排。通过上述步骤,我们分析并筛选了数据库中的730个配方,发现了30种最常用于治疗慢性胃炎的草药。通过应用改进的互信息测度,得到94种相关系数在0.05以上的常用药草。通过复杂系统的熵聚类方法,我们找到了11个核心组合。采用复杂系统的熵聚类方法建立了80种常用的治疗慢性胃炎的草药之间的关联,从而获得了122种关联。我们绘制了慢性胃炎常用草药的复杂网络图。这些结果与临床实践完全一致,实质上是高中英教授用于治疗慢性胃炎的常用草药。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号