Effect of Nigella sativa and bee honey on pulmonary, hepatic and renal function in Sudanese in Khartoum state

摘要

Nigella sativaseeds and Bee honey (BH) had been widely used in traditional medicine. In the present study we assessed their effect in treating asthma. A dose of 2 g of wholeN. sativaseeds and 1 teaspoon full of BH per day were taken by the subjects -5 asthmatics and 22 non-asthmatics, 8 to 40 years in Khartoum for three month. They were also asked to smell crushed seeds that were warped in porous cloth three times a day. We assessed the effects of both on pulmonary, renal and hepatic function. Regarding pulmonary function, there was a significant increase in forced vital capacity (FVC) (P=0.023) in asthmatics' group and peak expiratory flow rate (PEFR) (P = was 0.049) in non-asthmatics' group. For evaluating the toxicity of both renal and hepatic functions, both were assessed before and after treatment. Hepatic enzymes were spared whereas serum creatinine in non-asthmatics and blood urea in asthmatics and in those having upper limit blood urea decreased significantly (creatinine (P=0.049) and urea (P value = 0.023, 0.017, respectively). In conclusion bothN. sativaand BH seem to have some benefits to asthmatics with no hepato-renal toxicity.