Pharmacological screening of Morchella esculenta (L.) Pers., Calvatia gigantea (Batsch ex Pers.) Lloyd and Astraeus hygrometricus Pers., mushroom collected from South Waziristan (FATA.)

摘要

The mushrooms were screened for their antimicrobial, and cytotoxicity, six strains of bacteria viz.Staphylococcus aureus(ATCC6538),Bacillus subtilis(ATCC6633),Vibrio cholerae(ATCC6643),Escherichia coli(ATCC15224),Klebsiella pneumoniae(MTCC618)andEnterobacter aerogenes(ATCC13048) were utilized as test organisms for determination of antibacterial activity. Maximum antibacterial activity was observed at 30 mg/ml concentration of extracts. Greater inhibitory activity againstS. aureuswas possessed by methanolic and ethanolic extracts ofCalvatia gigantean. The methanolic extract ofMorchella esculentaexhibited maximum inhibitory activity againstV. choleraeand also the ethanolic extract showed higher bactericidal activity againstE. coli. But the selected mushrooms exhibited no significant antifungal activity againstAspergillus fumigatusandAspergillus niger.