ZOC-Catalyzed an efficient synthesis of 1, 5-Benzodiazepines under mild conditions

摘要

2,3-Dihydro-1H-1,5-benzodiazepines are synthesized by reaction of o-phenylenediamine with ketones (acyclic as well as cyclic) under mild and solvent free conditions in the presence of catalytic amount of zirconium oxychloride in short reaction time with excellent yield.